Rare Skin Disorder

A rare skin disorder is one which is very unusual and are caused by unusual factors which cannot be easily identified. These disorders occur as a result of some rare allergy or problem causing factors acting on the skin.

Some types of rare skin disorders

1. Epidermolysis Bullosa (EB)
It is an extremely rare case of skin disorder. The occurrence is just one in every two million infants. The skin peels off even with the slightest touch, causing open wounds. Since it is the rarest, the ones affected find it difficult to accept and cope up with it.

2. Pemphigus
It is a group of rare autoimmune skin disorder, where blisters occur on the outer layer of the skin (epidermis) and mucous membranes (thin, moist layers lining the body's internal surfaces). Blisters occur when the cement holding the cells together (called epidermal acantholysis) is destroyed causing the cells to separate form one another. The type of blisters and their location on the body may vary. Soft blisters are generally found on neck, scalp, mucous membranes and groin areas. It may turn into a serious illness, if left unattended. When the antibodies supposed to attack the foreign substances start attacking the healthy tissues in the body, autoimmune disorders occur, causing this condition. It can be treated with antibiotic drugs and creams (standard therapy) and by removal of unwanted substances from the blood (investigational therapy).

3. Bextra Stevens Johnson Syndrome
Caused by the use of Bextra (an anti-inflammatory drug used in treatment of osteoarthritis and rheumatoid arthritis), it is a serious skin reaction characterized by swelling in the mouth, throat, anogenital areas, intestinal tract and lining of eyelids. Flat or small and raised, purplish or red lesions that may develop into fluid-filled blisters, bleeding in the lips, mouth eyes, nasal passages are the symptoms.

4. Xeroderma pigmentosum (XP)
A group of rare inherited skin disorders where the skin reacts intensely to sunlight (photosensitivity), and skin blisters occur. At times, pain and blisters occur immediately after contact with sunlight. Acute sunburn, redness or skin inflammation, discoloration, weakness, scars on skin are the symptoms of XP. The symptoms may appear at birth or sometime later in the childhood or adulthood. Associated with several forms of skin cancers, it may affect the eyes and the skin, and may sometimes occur along with dwarfism, mental retardation, and/or delayed development.

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